Antinuclear Antibody (ANA) and Related Autoantibody Panel, Blood — Qualitative Probe
A blood test that evaluates ANA and related autoantibodies, including DNA, phospholipid, and Sm antibodies, to help assess possible autoimmune disease.
["A positive result may support an autoimmune condition, but it must be interpreted with your symptoms and other laboratory findings."]
Key facts at a glance
- LOINC
- 96312-4
- Short code
- S maltophilia DNA Bld Pos Ql NAA+non-prb
- Synonyms
- S maltophilia DNA Bld Pos Ql NAA+non-prb
- Category
- liver
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 7
- Ref high
- 56
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- non-probe-amp-tar
- CPT
- 84484
- SNOMED
- 302773008
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test examines blood for antinuclear antibodies and related autoantibodies. Depending on the ordered panel, it may include antibodies directed against DNA, phospholipids, or the Sm antigen.
Why might I need this test?
It may be ordered for symptoms that suggest an autoimmune condition, such as joint pain, skin rashes, fatigue, fever, or unexplained inflammation. The results help guide further evaluation but do not establish a diagnosis by themselves.
How is the test performed?
A blood sample is collected and tested in the laboratory for the presence of selected antibodies. This is a qualitative test, so results are generally reported as positive or negative rather than with a numeric measurement.
How do I prepare for the test?
Fasting is usually not required, but follow any instructions provided by your clinician or laboratory. Tell the healthcare team about autoimmune disease, recent infections, medications, and supplements, because these can affect interpretation.
Reference range
Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A positive ANA or related autoantibody result may occur in autoimmune disorders such as lupus, Sjögren syndrome, rheumatoid arthritis, or systemic sclerosis. However, these antibodies can also be present in healthy people, during some infections, or with certain medications. Results should therefore be interpreted by a clinician alongside symptoms, examination findings, and other tests.
Short name
ANA and autoantibody panel
Frequently asked questions
Does a positive result mean I have an autoimmune disease?
What is the difference between ANA and the other antibodies in the panel?
Can medications or infections affect the result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy