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: SNAP-25 Amplitude (Serum/Plasma) by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

: This test measures the amount of SNAP-25, a synaptic vesicle protein, in a serum or plasma sample using an immunoassay method. It is not a standard routine blood test and is used mainly in specialized research or neurology contexts.

Quick summary

[": SNAP-25 amplitude testing measures a neuronal protein in blood and is primarily a specialized or research-oriented test rather than a routine screening test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98659-6
Short code
SNAP amplitude L sural n
Synonyms
SNAP amplitude L sural n
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
nerve-conduction
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is SNAP-25?

: SNAP-25 (synaptosomal-associated protein 25) is a protein found at the junctions between nerve cells, where it helps vesicles release signaling molecules. Because small amounts can leak into the bloodstream, it can sometimes be measured in blood, but this is not a common clinical measurement.

: Why Might This Test Be Ordered?

: This test is generally used in research or specialty settings to study nerve-cell function or certain neurological conditions. It is not typically part of standard diagnostic panels, so your doctor would order it only for a specific reason that should be discussed with you.

: How the Sample Is Collected

: A standard blood draw from a vein provides the serum or plasma sample. No special preparation is usually required unless your care team instructs otherwise.

: Understanding Your Result

: Results are interpreted by the ordering clinician in the context of your symptoms, history, and other tests. Because this is a specialized measurement, there is no universal reference range that applies to everyone, so ask your provider what your result means for you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: NONE

Frequently asked questions

: Is this a routine blood test?
: No. SNAP-25 measurement in blood is a specialized or research-oriented test and is not part of standard screening panels.
: Do I need to fast before this test?
: Usually no special preparation is needed, but follow any instructions given by your healthcare provider or the laboratory.
: Can this test diagnose a neurological condition on its own?
: No. It is interpreted alongside your symptoms, history, and other tests; a single result cannot diagnose a condition by itself.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy