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Serum Area Under the Curve (AUC) for Lactate Dehydrogenase (LDH) over a specified time period (e.g., 24-hour)

Published: August 9, 2026Updated: August 16, 2026

This test measures how much LDH, an enzyme involved in energy production, changes over time in your blood. It helps assess conditions affecting red blood cells or muscle tissue.

Quick summary

["This test helps evaluate conditions linked to red blood cell breakdown or muscle damage by tracking enzyme levels over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98651-3
Short code
SNAP area AUC L LACN
Synonyms
SNAP area AUC L LACN
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
nerve-conduction
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like fatigue, shortness of breath, or muscle pain that could indicate conditions like anemia, infections, or certain cancers. It may also be used in monitoring certain treatments or conditions affecting blood cells or tissues.

What to Expect Before the Test

No special preparation is usually needed. You may have a blood draw from a vein in your arm. If you’re taking blood thinners or have a history of bleeding issues, let your provider know.

What the Test Results Mean

LDH levels can rise in conditions like blood disorders, heart attacks, liver disease, or infections. An AUC test helps track changes over time, which can be useful for diagnosing or managing these conditions.

Common Conditions Monitored

This test is often used to monitor conditions like hemolytic anemia (red blood cell destruction), certain cancers (e.g., lymphoma), or muscle injuries. It may also help assess liver or heart health in some cases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated LDH levels over time can signal ongoing damage to red blood cells, tissues, or organs. The AUC provides a clearer picture of progression or response to treatment, helping doctors make informed decisions about care.

Short name

Lactate Dehydrogenase AUC (Serum)

Frequently asked questions

What does a high LDH AUC mean?
A high AUC for LDH may indicate conditions causing red blood cell breakdown, muscle damage, or organ stress. Your provider will discuss results in the context of your symptoms and other tests.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab. Follow-up with your provider to discuss findings.
Can I eat or drink before this test?
You can eat and drink normally unless instructed otherwise. Avoid alcohol 24 hours before testing, as it may affect enzyme levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy