Serum Anti-Cardiolipin Antibody (IgG) by Immunoassay
This test measures the level of antibodies in your blood that target cardiolipin, a fatty substance found in cell membranes. These antibodies may be linked to certain autoimmune conditions.
["This test helps assess potential autoimmune or inflammatory conditions."]
Key facts at a glance
- LOINC
- 98662-0
- Short code
- SNAP area AUC L sural n
- Synonyms
- SNAP area AUC L sural n
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- nerve-conduction
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Anti-cardiolipin antibodies are proteins your immune system produces in response to cardiolipin, a phospholipid present in cell membranes. Elevated levels may be associated with autoimmune disorders, such as lupus or antiphospholipid syndrome, or other inflammatory conditions.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like unexplained blood clots, recurrent miscarriages, or other signs of autoimmune activity. It can also be part of screening for conditions like lupus or other connective tissue diseases.
How Is the Test Performed?
A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab for analysis using an immunoassay method to detect the presence of IgG antibodies against cardiolipin.
What Are Common Results?
Results are typically reported as a qualitative (positive/negative) or quantitative measurement of antibody levels. Interpretation depends on clinical context and may include comparison to reference ranges if available.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test helps identify individuals with elevated antibody levels that may indicate an autoimmune or inflammatory condition. While positive results can raise suspicion for conditions like antiphospholipid syndrome or lupus, they are not definitive on their own. Further evaluation, including clinical correlation and other tests, is often needed to diagnose specific conditions.
Short name
Anti-Cardiolipin Antibody IgG
Frequently asked questions
What does a positive result mean?
Can this test be used to diagnose lupus?
How often should I get this test retested?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy