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24-Hour Urinary Sodium Excretion Rate

Published: August 9, 2026Updated: August 16, 2026

This test measures how much sodium your body excretes in urine over a full day. It helps assess kidney function and how well your body regulates sodium balance.

Quick summary

["This test helps diagnose kidney issues or sodium imbalance over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
21527-7
Short code
Sodium 24h Ur-mRate
Synonyms
Sodium 24h Ur-mRate
Category
electrolyte
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84295
SNOMED
110741000
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms like high blood pressure, swelling, frequent urination, or signs of kidney problems. It can also help evaluate conditions like kidney disease, heart failure, or certain hormonal imbalances that affect sodium levels.

What Does the Test Involve?

You’ll collect all your urine for a full 24-hour period, typically starting after you urinate in the morning. The urine is then sent to the lab for analysis. The test measures the total sodium content in your urine over that time.

What Are Common Causes?

Conditions that may lead to this test include chronic kidney disease, heart failure, certain medications (like diuretics), or syndromes like Bartter syndrome or Gitelman syndrome, which affect sodium balance.

What If Results Are Abnormal?

High sodium excretion may suggest kidney issues, excessive sweating, or certain medications. Low sodium excretion could indicate kidney problems, dehydration, or conditions that restrict sodium loss (like certain hormonal disorders). Discuss any results with your doctor.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: urine

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test provides insight into how well your kidneys filter sodium and manage fluid balance. Abnormal results may indicate underlying conditions requiring medical attention, such as kidney dysfunction, electrolyte imbalances, or conditions affecting sodium retention or excretion.

Short name

24h Sodium Urine Rate

Frequently asked questions

How is the urine collection done?
You’ll need to collect every drop of urine for 24 hours, including during sleep. Use a clean container and record the time each urine sample is collected. Some labs may provide a 24-hour urine collection kit with instructions.
What should I avoid before the test?
Avoid excessive salt intake or certain medications (like diuretics) that may affect sodium levels unless instructed by your doctor. Also, drink enough water to maintain normal hydration but avoid overhydration.
Can I take this test at home?
Yes, many labs offer home urine collection kits for this test. Follow the instructions carefully to ensure accurate results. If you have any medical conditions or concerns, consult your doctor before starting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy