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Sodium [Substance Concentration] in Amniotic Fluid

Published: August 9, 2026Updated: August 16, 2026

This test measures the concentration of sodium, a key electrolyte, in a sample of amniotic fluid. It is used as part of the evaluation of amniotic fluid composition and fetal well-being.

Quick summary

["The test quantifies the amount of sodium dissolved in amniotic fluid."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49791-7
Short code
Sodium Amn-sCnc
Synonyms
Sodium Amn-sCnc
Category
electrolyte
Sample
fluid
Container
Sterile tube
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84295
SNOMED
110741000
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What Is Being Measured

Sodium is an electrolyte, a mineral that carries an electrical charge and helps regulate the balance of water in and around the body's cells. This test determines the substance concentration of sodium in amniotic fluid, which is the fluid surrounding a baby in the womb. The result reflects how much sodium is present in a defined volume of that fluid.

Why the Test Is Performed

Measuring sodium in amniotic fluid is generally done to assess the fluid's composition, often during procedures that evaluate fetal health or in research settings. It can provide information about electrolyte balance within the amniotic sac, which may be relevant when there are concerns about fetal kidney function or overall fetal well-being.

How the Sample Is Collected

A sample of amniotic fluid is collected by a procedure called amniocentesis. A healthcare provider inserts a thin needle through the abdominal wall into the uterus, guided by ultrasound, and withdraws a small amount of fluid. The sample is then sent to a laboratory for chemical analysis.

What the Result Means

Your provider interprets the sodium concentration in the context of the reason for testing, the gestational age, and other test results. There is no single universal reference range, so the laboratory's own reference intervals and your clinician's judgment should be used to interpret the value. Discuss any results directly with your healthcare team.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: fluid

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Amniotic Fluid Sodium

Frequently asked questions

Does this test hurt?
Amniocentesis involves a needle insertion, so you may feel a brief sting or cramping. Many providers use local anesthesia or simply quick technique. Discomfort is usually mild and short-lived, but discuss any concerns with your provider.
Do I need to fast before this test?
Fasting is generally not required for an amniotic fluid sodium measurement, but follow any specific instructions your healthcare provider gives you before the procedure.
Can I get results immediately?
No. The fluid sample must be processed and analyzed in a laboratory, so results typically take one to several days. Your provider will explain when to expect results and what they mean for your care.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy