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Sodium and Glucose in Serum (Plasma) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of sodium and glucose in your blood plasma or serum, which can help assess hydration status and metabolic health.

Quick summary

["Checks for dehydration, diabetes, or electrolyte imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51419-0
Short code
Sodium Glucose cor SerPl-sCnc
Synonyms
Sodium Glucose cor SerPl-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test evaluates two key substances: sodium, an electrolyte critical for fluid balance and nerve function, and glucose, the primary energy source for your body. Sodium levels help determine if you’re retaining or losing too much fluid, while glucose levels indicate how your body processes sugar.

Why It Matters in Your Health

Abnormal sodium levels may signal dehydration, kidney issues, or conditions like hyperaldosteronism. Elevated glucose could point to undiagnosed diabetes or insulin resistance, while low levels might suggest severe dehydration or metabolic disorders.

Common Reasons for Testing

Doctors may order this test if you have symptoms like excessive thirst, confusion, fatigue, frequent urination, or unexplained weight changes. It’s also used in monitoring chronic conditions like heart failure, kidney disease, or diabetes.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate plasma or serum for testing. You may be asked to fast before the test if glucose levels are being specifically measured, but sodium levels are generally tested on any blood sample.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: serum

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum/plasma sodium-glucose profile

Frequently asked questions

How might abnormal results affect my treatment?
Abnormal sodium levels may require adjustments to your fluid intake, medications (like diuretics or steroids), or further evaluation for underlying conditions. Glucose results could prompt lifestyle changes (like diet or exercise) or medical interventions if diabetes is suspected. Always discuss findings with your healthcare provider to tailor your care plan.
Can I eat or drink anything before this test?
For sodium levels alone, no special preparation is needed. If glucose is part of the test, your provider may instruct you to fast for 8–12 hours before the blood draw to get more accurate results. Follow your provider’s specific instructions.
How long will I need to wait for results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will explain the findings and next steps during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy