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Sodium concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of sodium, a key mineral, in your blood plasma or serum. Sodium helps regulate fluid balance, nerve and muscle function, and blood pressure.

Quick summary

["Sodium levels help doctors check for dehydration, kidney issues, or conditions like high blood pressure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111263-0
Short code
Sodium Msmt Stl
Synonyms
Sodium Msmt Stl
Category
electrolyte
Sample
stool
Container
Clean container
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84295
SNOMED
110741000
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a sodium test to diagnose or monitor conditions such as dehydration (from vomiting, diarrhea, or excessive sweating), kidney problems, or hormonal imbalances like hyperaldosteronism. It can also help assess fluid shifts in severe illnesses or after certain treatments.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the blood draw, but this depends on your doctor’s instructions. Avoid excessive salt intake 24 hours before testing if advised.

What Happens During the Test?

A healthcare provider will take a small blood sample from a vein in your arm. The sample is sent to a lab for analysis. The test is quick and typically painless, though you may feel a slight pinch during the draw.

What Do Results Mean?

Results are compared to a standard range for healthy adults, but exact values can vary by lab. Low sodium (hyponatremia) may cause headaches, confusion, or muscle cramps, while very high sodium (hypernatremia) could lead to thirst, dry mouth, or irregular heartbeat.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: stool

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal sodium levels can signal serious underlying issues. Low sodium often results from excessive water retention, kidney dysfunction, or certain medications. High sodium may indicate dehydration, kidney disease, or overuse of salt or diuretics. Always discuss results with your doctor to understand the full picture.

Short name

Serum Sodium

Frequently asked questions

How long does it take to get my sodium test results?
Results are usually available within 1–3 business days, depending on your lab and healthcare provider. Some labs may provide results sooner, especially if follow-up is needed immediately.
Can I eat or drink before my sodium test?
Follow your doctor’s instructions, but generally, you may drink water unless fasting is required. Avoid excessive salt intake 24 hours before testing if advised.
What causes sodium levels to be too high or too low?
High sodium (hypernatremia) can result from dehydration, kidney problems, or excessive salt intake. Low sodium (hyponatremia) may stem from overhydration, kidney failure, or certain medications like diuretics or anticholinergics. Lifestyle factors, such as sweating excessively or poor kidney function, also play a role.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy