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Serum/plasma sodium and potassium concentration profile (24-hour profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures your body’s levels of sodium and potassium over a 24-hour period to assess how well your kidneys are balancing these essential electrolytes.

Quick summary

["Understanding how your electrolytes fluctuate can help identify kidney function and fluid balance issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74353-4
Short code
Sodium + Potassium Pnl Bld-sCnc
Synonyms
Sodium + Potassium Pnl Bld-sCnc
Category
electrolyte
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84295
SNOMED
110741000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like unusual thirst, swelling, muscle weakness, confusion, or irregular heartbeat. It’s also used to monitor kidney function, heart health, or conditions like hypertension or kidney disease.

What to Expect Before the Test

No special preparation is needed, but you may be asked to avoid certain medications or foods for a short time. Drink plenty of water unless instructed otherwise, as it helps your body’s natural electrolyte balance.

What the Test Involves

A healthcare provider will draw blood from a vein in your arm. You may feel a small pinch, but it usually takes only a few minutes. If you’re taking a 24-hour urine test for electrolytes, you’ll collect urine in a special container over 24 hours.

What the Results Mean

Your results will show how much sodium and potassium are in your blood or urine over time. Abnormal levels can indicate problems with kidney function, heart rhythm, or fluid balance, but exact values aren’t provided here—your doctor will interpret them with your symptoms and medical history.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Sodium/Potassium Profile

Frequently asked questions

How do I know if my electrolytes are balanced?
Your doctor will compare your test results to your overall health, symptoms, and lab history. For example, consistently high or low sodium/potassium levels may suggest kidney issues, dehydration, or heart problems. This test helps track trends over time rather than single-point measurements.
What if I have kidney disease?
If you have kidney disease, your doctor may use this test to monitor how well your kidneys are filtering electrolytes. Fluctuations in sodium/potassium can signal worsening kidney function or the need for adjustments to medications like diuretics or blood pressure drugs.
Can diet affect these results?
Yes, diet plays a role. High sodium intake (from processed foods) or low potassium intake (from certain fruits/vegetables) can temporarily alter levels. Since this is a 24-hour profile, it reflects your natural balance rather than short-term dietary spikes. Discuss your diet with your doctor if results seem unusual.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy