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Sodium concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of sodium, a key mineral, in your blood. Sodium helps balance fluids and maintain normal blood pressure.

Quick summary

["Sodium levels help doctors check if you have too much or too little sodium in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49790-9
Short code
Sodium Prt-sCnc
Synonyms
Sodium Prt-sCnc
Category
electrolyte
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84295
SNOMED
110741000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Sodium is vital for many bodily functions, including nerve and muscle activity, fluid balance, and blood pressure regulation. Abnormal levels can cause serious health issues, such as dehydration, swelling, or heart problems. Your doctor may order this test to diagnose or monitor conditions like kidney disease, heart failure, or excessive sweating.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or vein to draw blood. If you’re on a sodium-restricted diet, let your doctor know before the test.

Possible Causes of Abnormal Results

High sodium levels (hypernatremia) may occur from dehydration, excessive salt intake, or kidney problems. Low sodium levels (hyponatremia) can result from excessive sweating, vomiting, diarrhea, or certain medications. Your doctor will discuss symptoms and other test results to determine the cause.

Common Conditions Monitored

Doctors often check sodium levels in patients with symptoms like confusion, swelling, rapid heartbeat, or unexplained weight gain. It’s also used to monitor people with chronic conditions like heart failure, liver disease, or kidney problems.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Sodium Level

Frequently asked questions

What does a low sodium level mean?
A low sodium level (below normal) can indicate conditions like dehydration, excessive sweating, or certain medications that cause fluid retention. It may also signal kidney issues or hormonal imbalances. Your doctor will review your symptoms, other test results, and medical history to understand the cause.
What does a high sodium level mean?
A high sodium level (above normal) may suggest dehydration, excessive salt intake, or kidney or heart problems. It can also occur in people with diabetes insipidus or certain hormonal disorders. Your doctor will assess your overall health and other factors to determine the reason.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition, symptoms, and treatment plan. Regular monitoring may be needed if you have chronic illnesses like heart failure, kidney disease, or liver disease.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy