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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood serum. It helps assess kidney function by tracking how well your kidneys filter blood.

Quick summary

["Creatinine levels help determine kidney health and guide treatment for conditions like kidney disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99768-4
Short code
Sol Il2 Recep CSF-mCnc
Synonyms
Sol Il2 Recep CSF-mCnc
Category
coagulation
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for kidney problems, monitor kidney function over time, or evaluate symptoms like fatigue, swelling, or changes in urine output. It’s also used before certain procedures or surgeries to assess overall kidney health.

What Does a High or Low Level Mean?

High creatinine levels may indicate poor kidney function, while low levels could suggest overhydration, muscle loss, or other conditions. However, results alone don’t diagnose kidney disease—your provider will consider other factors.

How Is This Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed to measure creatinine concentration using a specialized method, often enzymatic or nephelometric techniques.

What Are Common Causes of Abnormal Results?

Factors like dehydration, muscle injury, or certain medications can temporarily affect creatinine levels. Chronic kidney disease, diabetes, or heart conditions may also lead to consistently elevated levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine (Serum)

Frequently asked questions

What does a normal creatinine level mean for my health?
A normal result doesn’t guarantee healthy kidneys on its own, but it suggests your kidneys are filtering blood effectively. Your provider will use this test along with other information to assess your overall kidney health.
How often should I get this test?
Your provider will determine the frequency based on your medical history, symptoms, and other tests. Regular monitoring may be needed if you have kidney-related conditions or risk factors.
Can diet or exercise affect creatinine levels?
Dietary protein intake and muscle mass can influence creatinine levels. High-protein diets or muscle loss may temporarily raise levels, while hydration status also plays a role. Always discuss dietary changes with your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy