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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green (BCG) dye binds to a protein in your blood, often used to assess liver function or protein synthesis.

Quick summary

["A BCG dye binding test helps doctors check liver health or protein levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34408-5
Short code
Sol Il2 Recep SerPl-sCnc
Synonyms
Sol Il2 Recep SerPl-sCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The BCG dye binding test works by mixing a dye (bromocresol green) with your blood sample. Healthy proteins in your blood bind to the dye, changing its color. The test measures how much dye binds, which can reflect liver function or protein production.

Why It’s Done

Doctors may order this test if you have symptoms like jaundice (yellowing skin), unexplained weight loss, fatigue, or if they suspect liver disease, protein disorders, or other conditions affecting protein synthesis.

Sample Collection

Blood is drawn from a vein, usually in your arm. The sample is sent to a lab where it’s tested for how well the dye binds to proteins.

What to Expect Before the Test

No special preparation is needed, but inform your doctor about any medications or conditions that might affect results, such as liver disease or certain blood disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Dye Binding Assay

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times.
What does a low or high result mean?
A low result may signal liver problems or protein deficiency, while a high result is less frequently discussed but could relate to specific protein abnormalities—results should always be interpreted by your healthcare provider.
Can I eat or drink before this test?
You can eat and drink normally unless your doctor specifies otherwise, as no fasting is required for this test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy