Serum/Plasma Line Blot for Soluble Liver Injury Markers
This test detects specific proteins released when liver cells are damaged, helping identify potential liver issues.
["Assesses subtle liver damage through protein markers in your blood."]
Key facts at a glance
- LOINC
- 78433-0
- Short code
- Soluble liver IgG Ser Ql Line blot
- Synonyms
- Soluble liver IgG Ser Ql Line blot
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- line-blot
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
A line blot assay evaluates the presence of soluble liver injury markers (such as proteins like MCTP or other stress-induced proteins) in your serum or plasma. This method visually identifies bands corresponding to these markers, aiding in early detection of liver stress or damage beyond traditional enzyme tests.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like fatigue, jaundice, or unexplained liver-related concerns, or if standard liver function tests (like ALT or AST) show mild abnormalities. It can also be used in research or specialized settings to monitor chronic liver conditions.
Common Uses in Clinical Practice
This test is less commonly used in routine clinical settings compared to standard liver function tests but may be part of advanced diagnostic workups for conditions like chronic hepatitis, fatty liver disease, or autoimmune liver disorders where traditional markers are inconclusive.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample, typically drawn from your arm in a clinic or lab. If you’re on blood thinners, inform your provider beforehand.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Soluble liver injury markers detected by this test can indicate subtle or chronic liver stress, which may not be captured by traditional liver enzymes alone. Elevated levels may suggest conditions like chronic hepatitis, non-alcoholic fatty liver disease, or early-stage cirrhosis, helping guide treatment decisions or monitor disease progression.
Short name
Liver Injury Screening (Line Blot)
Frequently asked questions
How long will results take to return?
Can this test replace standard liver function tests?
What if my results are abnormal?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy