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Ragweed-specific Immunoglobulin E (IgE) Antibody, Serum

Published: August 9, 2026Updated: August 17, 2026

This test measures your body’s immune response to ragweed pollen, helping identify allergies that may cause seasonal symptoms like sneezing, itching, or breathing difficulties.

Quick summary

["This test helps diagnose ragweed allergies and guides treatment options."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102560-0
Short code
Southern Ragweed IgE RAST
Synonyms
Southern Ragweed IgE RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Ragweed is a common allergen that triggers allergic reactions in many people, especially during late summer and early fall. This test checks for IgE antibodies—proteins your immune system produces in response to ragweed exposure. High levels may indicate an allergy that could affect your daily life or require medical attention.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test is quick and typically done at a lab or clinic. If you’re taking blood thinners or have a history of bleeding disorders, let your provider know.

How the Test Works

Your blood sample is tested using an immunoassay method to detect IgE antibodies specific to ragweed pollen. The test measures the concentration of these antibodies, which your immune system produces when it recognizes ragweed as a threat.

Possible Results and Next Steps

Results are interpreted by your healthcare provider. Elevated IgE levels suggest an allergic reaction to ragweed. They may recommend allergy testing, immunotherapy (like allergy shots), or other treatments to manage symptoms. Follow-up may include allergy testing with skin prick tests or further bloodwork.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgE to Ragweed

Frequently asked questions

What does a positive result mean?
A positive result (elevated IgE levels) strongly suggests an allergic reaction to ragweed pollen. This can lead to symptoms like hay fever, asthma flare-ups, or skin reactions. Your doctor may use these results to tailor treatments, such as avoiding ragweed exposure, using antihistamines, or starting allergy immunotherapy.
Can this test predict future allergies?
This test helps confirm an existing allergy but doesn’t predict future reactions. If you suspect ragweed allergies, it’s best to discuss results with your doctor. They may recommend additional tests or monitoring to track symptoms over time.
How often should I get this test?
The frequency depends on your symptoms and medical history. If you’ve been diagnosed with ragweed allergies, your doctor may recommend retesting every few years or as needed to monitor changes in your immune response. Always follow your healthcare provider’s guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy