Serum or Plasma Albumin to Globulin Ratio (A/G Ratio)

What Does This Test Measure?

Albumin and globulin are two types of proteins found in your blood. Albumin helps maintain fluid balance in your body, while globulins are involved in immune function and transport of substances like hormones and metals. The A/G ratio evaluates the proportion of these proteins, which can reflect conditions like malnutrition, liver disease, or kidney problems.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if they suspect liver disease, kidney disease, or protein malnutrition. It can also be used to monitor chronic conditions like cirrhosis or chronic kidney disease.

How Is the Test Performed?

A small blood sample is taken from a vein in your arm. The blood is then processed to separate and measure albumin and globulin levels. The ratio is calculated by dividing albumin concentration by globulin concentration.

What Are Common Results and Their Meanings?

A higher A/G ratio may suggest liver disease, malnutrition, or chronic inflammation, while a lower ratio could indicate kidney disease or severe protein loss. However, results depend on individual health and should be interpreted by a healthcare provider.