Vagus nerve stimulation stress test (plasma)

What Does This Test Measure?

The vagus nerve stimulation stress test evaluates the activity of your vagus nerve by measuring specific physiological responses in plasma. It typically involves applying gentle stimulation to the nerve and assessing changes in biomarkers that reflect autonomic nervous system activity, such as certain hormone or enzyme levels.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have symptoms like unexplained dizziness, irregular heartbeat, or digestive issues that suggest problems with your autonomic nervous system. It can also be used to monitor conditions like autonomic neuropathy or evaluate responses to treatments.

How Is the Test Performed?

You’ll likely lie down while a healthcare professional gently stimulates the vagus nerve—often through the carotid sinus (near your neck) or by applying pressure to the inner thigh. Blood is drawn before and after stimulation to compare levels of specific analytes in your plasma.

What Does the Test Result Mean?

Results are interpreted based on how your body’s biomarkers change in response to stimulation. A normal response would show predictable shifts in your plasma levels, while abnormal patterns may indicate dysfunction in your nervous system.