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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42310-3
Short code
SPECT Kidney W RNC IV
Synonyms
SPECT Kidney W RNC IV
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
nm-spect
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test measures the amount of creatinine in your blood, which helps show how well your kidneys are filtering waste from your body. Your provider may order it to check kidney function, monitor known kidney disease, or see how certain medicines are affecting your kidneys over time.

Creatinine levels can indicate how well your kidneys are working. High levels may suggest kidney damage or disease, while low levels could indicate dehydration or other conditions. Your doctor may order this test to monitor kidney health, especially if you have risk factors like diabetes, high blood pressure, or a family history of kidney problems.

In most cases, you can eat and drink normally before this blood test, but your provider may ask you to avoid eating a lot of meat or taking certain supplements beforehand. Tell your care team about all medicines you take, and drink water unless you are told otherwise.

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a larger panel. Drink plenty of water the day before to help dilute creatinine levels if needed. Avoid heavy exercise or strenuous activity 24 hours prior.

A nurse or technician will draw a small sample of blood, usually from a vein in your arm. The process takes only a few minutes. You may feel a quick pinch or sting when the needle goes in, and a small bandage will be placed on the spot afterward.

A healthcare professional will draw blood from a vein in your arm. The process takes a few minutes and may cause a slight pinch. You’ll feel no discomfort afterward.

Your results usually come back within a day or two, and normal ranges can vary by lab, age, sex, and muscle mass. If your creatinine is high, your provider may order additional tests, adjust your medicines, or talk with you about protecting your kidneys. Low results are often harmless but may still need follow-up.

Results are typically reported in milligrams per deciliter (mg/dL). Your doctor will compare your result to your baseline and any risk factors you have. If levels are abnormal, follow-up tests or treatments may be recommended to address kidney function or underlying causes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine Level

Frequently asked questions

What does a high creatinine level mean?
A low creatinine level often simply reflects low muscle mass, which is common in older adults or people with less body muscle. Less often, it can be linked to liver disease, malnutrition, or pregnancy, so your provider will review your overall health before deciding whether more testing is needed.
How often should I get this test?
Yes, diet can play a role. Eating large amounts of cooked meat shortly before the test may temporarily raise creatinine, while a low-protein diet or significant weight loss can lower it. Staying well hydrated also matters, so follow any eating and drinking instructions your care team gives you before testing.
Is there anything I should avoid before the test?
Avoid heavy exercise, large protein meals, or excessive alcohol 24 hours before testing. Some medications (like NSAIDs) may also affect results, so check with your provider if you’re on long-term medications.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy