Sperm Morphology Analysis (Quantitative Head Defect Count)
This test examines the shape and structure of your sperm cells, focusing on the proportion of sperm with abnormal heads. Abnormal sperm heads may affect fertility.
["Abnormal sperm head shapes could impact your ability to conceive."]
Key facts at a glance
- LOINC
- 10606-2
- Short code
- Sperm Amorphous Head NFr Smn
- Synonyms
- Sperm Amorphous Head NFr Smn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
A sperm head defect is counted as part of a broader sperm morphology assessment. This test specifically evaluates the frequency of sperm with irregular head shapes, which may be detected under a microscope. While not all sperm defects are linked to fertility issues, certain patterns (like those seen in conditions like Klinefelter syndrome) can be associated with reduced fertility or chromosomal abnormalities.
Why It’s Done
Your healthcare provider may order this test as part of a fertility evaluation, especially if you’ve experienced difficulty conceiving. It can also be included in routine semen analysis when assessing sperm quality for couples undergoing fertility treatments or those with known genetic concerns.
How It’s Performed
A semen sample is collected and examined under a microscope. The test counts a specific subset of sperm with abnormal head shapes, often as part of a broader morphology assessment (e.g., World Health Organization criteria). Results are reported as a percentage of total sperm cells with defects.
What the Results Mean
Results are typically expressed as a percentage of sperm with abnormal heads. While there are no universally accepted reference ranges for this specific defect alone, high percentages may correlate with fertility challenges. Your doctor will interpret results in the context of your overall semen analysis and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
What questions might you have about this test?
How often should I get this test?
Can lifestyle changes affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy