Sperm IgA (Immunoglobulin A) Content in Semen
This test measures the amount of Immunoglobulin A (IgA), a type of antibody found in semen, which may play a role in immune function within the reproductive tract.
["IgA in semen can help assess immune response and potential fertility-related factors."]
Key facts at a glance
- LOINC
- 106119-1
- Short code
- Sperm IgA NFr Smn
- Synonyms
- Sperm IgA NFr Smn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
IgA is a type of antibody produced by the immune system. In semen, IgA may contribute to protecting the reproductive tract from infections. This test specifically evaluates the concentration of IgA in semen fluid, which can sometimes be measured as part of broader fertility evaluations or immune function studies.
Why Might This Test Be Ordered?
A healthcare provider may order this test if you are experiencing fertility issues, recurrent infections in the reproductive tract, or if there is suspicion of immune-related factors affecting semen quality. It may also be part of a broader evaluation for unexplained infertility or immune-mediated conditions.
How Is the Test Performed?
A semen sample is collected through masturbation or other standard methods, then analyzed in a laboratory. The test measures the concentration of IgA in the semen fluid using immunoassay techniques, which detect and quantify antibodies present.
What Are Common Reasons for Abnormal Results?
Abnormal IgA levels in semen could suggest immune dysfunction, chronic infections, or other underlying conditions affecting reproductive health. However, IgA alone is not typically used to diagnose fertility issues; results are usually interpreted alongside other clinical findings.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Understanding IgA in Semen
Short name
Semen IgA Level
Frequently asked questions
How does semen IgA testing differ from other antibody tests (e.g., in blood)?
What should I do if my IgA levels are low or high?
Can diet or supplements affect semen IgA levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy