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Sperm Immunoglobulin G (IgG) Content (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody found in sperm, which may be evaluated in certain fertility assessments.

Quick summary

["IgG in sperm can help assess immune-related factors in fertility."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33318-7
Short code
Sperm IgM Ser Ql
Synonyms
Sperm IgM Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you or your partner are experiencing unexplained infertility, recurrent pregnancy loss, or if there are concerns about immune-mediated issues affecting fertility. It may also be part of a broader evaluation for conditions like autoimmune disorders or sperm dysfunction linked to immune responses.

What to Expect Before the Test

No special preparation is typically required. You may provide a blood sample (serum or plasma) during a routine clinic visit. If testing sperm separately, follow your provider’s instructions for sample collection (e.g., masturbation into a sterile container).

How the Test Works

The test detects IgG antibodies in either your blood serum/plasma or sperm sample using an immunoassay method. This measures how much IgG is present, which can indicate immune activity or potential interference with fertility.

What the Results Mean

Results are not typically provided as a single numeric range for this specific test. Instead, they may be interpreted in relation to clinical context, such as whether IgG levels are elevated or low compared to expected baseline levels for sperm or blood samples.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG in Sperm

Frequently asked questions

What Does This Test Measure?
This test quantifies the presence of Immunoglobulin G (IgG) antibodies in either your blood serum/plasma or sperm sample. It helps evaluate potential immune-related factors that may impact fertility.
How Often Is This Test Used?
This test is less commonly performed than standard fertility tests like sperm count or hormone panels. It may be used in specialized fertility clinics or when investigating unexplained infertility or autoimmune-related concerns.
Can I Fast Before This Test?
No fasting is required for blood-based IgG testing. For sperm testing, follow your provider’s instructions regarding timing or sample collection methods.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy