Sperm Non-Prognostic Factor Screening (Sperm Profile Analysis)
This test evaluates various factors in your semen sample that may influence fertility, though some results do not directly predict pregnancy success.
["Understanding your semen health can help guide reproductive planning, though pregnancy depends on multiple factors beyond lab results alone."]
Key facts at a glance
- LOINC
- 10620-3
- Short code
- Sperm Nonprog NFr Smn
- Synonyms
- Sperm Nonprog NFr Smn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
A semen analysis typically includes measurements of volume, concentration, motility, morphology, and sometimes additional factors like pH or white blood cell counts. The 'non-prognostic' portion focuses on components that don’t strongly correlate with pregnancy likelihood, such as specific protein markers or cellular characteristics that may indicate health but don’t predict fertility outcomes directly.
Why Some Results Are Called 'Non-Prognostic'
Some measured factors in semen are included for completeness—like certain protein levels or cellular counts—to assess overall semen quality. However, these may not strongly predict whether pregnancy will occur. For example, while abnormal sperm morphology might suggest subfertility, it doesn’t always mean pregnancy will fail.
How This Test Differs from Standard Fertility Assessments
Unlike standard fertility tests (such as hormone panels or ovulation tests), this test focuses solely on semen characteristics. It’s often used alongside other evaluations to provide a broader picture of reproductive health, but results alone don’t guarantee pregnancy success.
What to Expect Before the Test
You’ll need to provide a fresh semen sample (typically collected by masturbation) after abstaining from ejaculation for 2–5 days. Avoid alcohol, caffeine, or strenuous activity before testing. Your provider may give specific instructions based on your situation.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Frequently asked questions
Does this test help predict pregnancy?
What if my results are abnormal?
Can I use this test to track fertility over time?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy