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Progesterone, Sperm-Associated (24-Hour Urine Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone found in your urine over a 24-hour period, often linked to reproductive health assessments in sperm-related evaluations.

Quick summary

["Progesterone levels in urine can help assess hormone balance, especially in fertility or sperm health contexts."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38501-3
Short code
Sperm Prog 2 NFr Smn
Synonyms
Sperm Prog 2 NFr Smn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’re investigating fertility issues, evaluating hormone imbalances, or assessing sperm quality. It can also be part of a broader evaluation for conditions affecting reproductive health.

What to Expect Before the Test

You’ll need to collect all urine for 24 hours, typically starting after waking up. Store the urine in a refrigerator or freezer to preserve the sample. Follow your provider’s instructions precisely for accurate results.

How the Test Works

Urine is analyzed to detect progesterone, a hormone involved in reproductive cycles. The test measures total excretion over a full day, providing a comprehensive picture of your hormone levels.

What the Results Mean

Results are compared to reference ranges specific to your age, sex, and clinical context. Abnormal levels may indicate hormonal imbalances, fertility challenges, or other reproductive health concerns.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Progesterone plays a critical role in reproductive function, including ovulation, sperm maturation, and potential pregnancy support. Elevated or low levels may signal underlying conditions requiring further evaluation by a healthcare provider.

Frequently asked questions

What causes abnormal progesterone levels in urine?
Abnormal levels can result from hormonal imbalances, conditions like polycystic ovary syndrome (PCOS), pregnancy, or medications affecting hormone production. Lifestyle factors, such as stress or diet, may also influence results.
How long does it take to get results?
Test results typically take 3–7 business days to process and return, depending on lab workflows and your provider’s communication method.
Can I take medications before this test?
Some medications may interfere with progesterone detection. Always inform your provider about all medications, supplements, or herbal products you’re taking before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy