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Progesterone concentration in semen fluid (confirmed)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone, in your semen fluid. Progesterone is involved in reproductive health and may be checked as part of fertility evaluation.

Quick summary

["Progesterone in semen can help assess male fertility and hormone balance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57443-4
Short code
Sperm Prog 3 p conc NFr Smn
Synonyms
Sperm Prog 3 p conc NFr Smn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re experiencing fertility issues, unexplained low sperm count, or other reproductive concerns. Progesterone levels in semen can provide clues about hormone function and potential fertility challenges.

What to Expect Before the Test

No special preparation is needed. You’ll provide a semen sample (usually collected via masturbation) in a sterile container. The sample is then analyzed for hormone concentration.

How the Test Works

A laboratory uses a sensitive immunoassay (or similar method) to detect and quantify progesterone in the semen fluid. The test measures its concentration in a specific unit (e.g., nanograms per milliliter).

What the Results Mean

Results help evaluate whether hormone levels in semen are within expected ranges for fertility. Abnormal levels may indicate hormonal imbalances that could affect sperm quality or reproductive health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Semen Progesterone Level (Confirm)

Frequently asked questions

What causes abnormal progesterone levels in semen?
Abnormal levels may result from conditions like polycystic ovary syndrome (in men), hormonal medications, or genetic factors. Stress, obesity, or exposure to endocrine-disrupting chemicals can also play a role.
How often should I get this test?
Your provider will determine frequency based on your symptoms, medical history, and fertility evaluation needs. Repeat testing may be recommended if initial results are concerning or if treatment is underway.
Can diet or lifestyle changes affect semen progesterone levels?
Yes—diet high in healthy fats, antioxidants, and vitamins (e.g., zinc, vitamin E) may support hormone balance. Avoiding alcohol, smoking, and excessive stress can also help maintain normal levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy