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Sperm Protein Profile Concentration (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the concentration of specific proteins found in semen, which can help evaluate sperm function, health, and potential fertility issues.

Quick summary

["This test assesses key protein markers in semen to support fertility evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
68915-8
Short code
Sperm Prog p conc NFr Smn
Synonyms
Sperm Prog p conc NFr Smn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you or a partner are experiencing difficulties conceiving. It can help identify whether sperm quality or function is affected by certain conditions, genetic factors, or exposure to toxins.

What the Test Involves

A semen sample is collected and analyzed for protein concentrations using advanced laboratory techniques. The sample is typically processed and tested within hours of collection to ensure accurate results.

What the Results Mean

The results provide a profile of protein levels that may indicate normal sperm health, potential abnormalities, or underlying issues affecting fertility. Interpretation depends on clinical context and comparison with known reference ranges for healthy samples.

Preparation for the Test

No special preparation is needed. You will be instructed to collect a semen sample at a clinic or lab on the day of testing. Avoid ejaculation for at least 2–3 days before the test if advised by your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

This test can help diagnose conditions such as genetic disorders, chronic infections, or exposure to environmental toxins that may impair sperm production or function. It may also be used to monitor treatment effectiveness for fertility-related conditions.
This test is not a standalone fertility solution but supports a broader evaluation alongside other tests like sperm count or motility assessments.
How long will I need to wait for results?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will discuss findings with you during a follow-up visit.
Is this test covered by insurance?
Check with your insurance provider to confirm coverage, as fertility-related tests may vary in coverage terms. Some plans may require prior authorization.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy