Sperm Protein Profile: Concentrations of Seminal Plasma Proteins
This test measures the levels of specific proteins found in semen, which can help assess sperm health, motility, and potential fertility issues. It may also be used in cases of unexplained infertility or to evaluate male reproductive function.
["This test helps evaluate sperm quality and reproductive health by examining protein concentrations in semen."]
Key facts at a glance
- LOINC
- 57456-6
- Short code
- Sperm Prog p conc # Smn
- Synonyms
- Sperm Prog p conc # Smn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you or your partner are experiencing fertility challenges, unexplained infertility, or if you have symptoms like low sperm count, abnormal semen analysis results, or recurrent pregnancy loss. It may also be part of a broader evaluation for conditions affecting male reproductive health.
What to Expect Before the Test
No special preparation is typically required. You may be asked to provide a semen sample, usually collected through masturbation into a sterile container. Follow your healthcare provider’s instructions for timing and collection to ensure accurate results.
What the Test Measures
This test analyzes the concentrations of key proteins in seminal plasma, which include enzymes, antioxidants, and other molecules that support sperm function. These proteins can reflect the health of sperm cells, their ability to move, and their potential to fertilize an egg.
How the Results Are Used
The results help identify imbalances in seminal proteins that may indicate underlying issues, such as poor sperm quality, inflammation, or hormonal imbalances. This information can guide treatment options, such as lifestyle changes, medical interventions, or further diagnostic testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal protein concentrations in semen can signal problems like oxidative stress, infection, or genetic factors affecting sperm. Elevated or low levels of certain proteins may correlate with reduced fertility, recurrent miscarriages, or other reproductive health concerns. This test is often used alongside other fertility assessments to provide a comprehensive evaluation.
Short name
Seminal Protein Analysis
Frequently asked questions
What does a normal range of these proteins mean for fertility?
How long does it take to get results from this test?
Can lifestyle changes affect the results of this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy