Skip to content

Sperm Progesterone Level (Washed Sperm)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone in sperm cells after washing, which may help assess reproductive health or hormone balance in male fertility evaluations.

Quick summary

["Progesterone in sperm could influence fertility and hormone function—this test provides a focused look at its role in male reproductive biology."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43377-1
Short code
Sperm Prog Pre Wash Smn Ql
Synonyms
Sperm Prog Pre Wash Smn Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’re experiencing fertility challenges, unexplained infertility, or if hormonal imbalances are suspected. It can also be part of a broader evaluation for conditions affecting sperm quality or reproductive health.

What to Expect Before the Test

During the test, semen is processed to remove fluids, leaving only sperm cells. Progesterone levels in these cells are then measured using a specialized laboratory technique.

What the Results Mean

High or low levels of progesterone in sperm may suggest hormonal imbalances, genetic factors, or other conditions affecting fertility. Your provider will discuss these findings in the context of your full medical history.

Clinical Significance

This test is often used alongside other fertility assessments, such as semen analysis or hormone panels, to provide a comprehensive evaluation of male reproductive function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Washed Sperm Progesterone

Frequently asked questions

What does a high progesterone level in sperm mean?
A high level may indicate hormonal imbalances, such as excess estrogen or pituitary dysfunction, which could influence sperm production or quality. It may also suggest conditions like hyperprolactinemia or other endocrine disorders.
What does a low progesterone level in sperm mean?
A low level may suggest androgen deficiency, genetic factors affecting hormone metabolism, or other reproductive health concerns. It could also be part of a broader evaluation for unexplained infertility.
Is this test painful or uncomfortable?
No, this test involves a semen sample collected during ejaculation, similar to a standard semen analysis. After collection, the sample is processed in the lab to analyze sperm cells without further patient discomfort.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy