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Serum Creatinine with Glomerular Filtration Rate (GFR) Estimation (using a modified equation)

Published: August 9, 2026Updated: August 16, 2026

This test measures your serum creatinine level and calculates an estimate of your kidney function using a specialized formula.

Quick summary

["Assess kidney health and function with a single test panel."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86020-5
Short code
S pn Da sero 19F Ab Ser-mCnc
Synonyms
S pn Da sero 19F Ab Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Your serum creatinine level reflects how well your kidneys filter waste products from your blood. The test also estimates your glomerular filtration rate (GFR), a key measure of kidney function, based on your creatinine level, age, sex, and race.

Why Is This Test Important?

High creatinine levels or low GFR may indicate kidney damage or disease, which can affect overall health and require medical attention. This test helps doctors monitor kidney function, especially in people with diabetes, hypertension, or other risk factors.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The serum portion is analyzed to determine creatinine concentration and GFR estimation.

What Are Common Results?

Results are reported as a creatinine value (in mg/dL) and an estimated GFR (in mL/min/1.73 m²). While reference ranges vary by lab, abnormal results may signal impaired kidney function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine & GFR Profile

Frequently asked questions

What Does a High or Low Result Mean?
Elevated creatinine or low GFR may indicate kidney disease, fluid overload, or dehydration. Low levels could suggest overhydration or kidney underperformance. Always discuss results with your healthcare provider.
How Often Should I Get This Test?
Your doctor may recommend this test periodically if you have kidney-related conditions, diabetes, high blood pressure, or other health concerns. Follow their guidance for timing and frequency.
What Can Affect My Results?
Factors like dehydration, muscle mass, diet (especially protein intake), and certain medications can influence creatinine levels. Avoid heavy exercise or high-protein meals before testing if instructed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy