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Serotype-specific immunoglobulin G (IgG) antibodies to pneumococcal bacteria (serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures your immune system’s response to different types of pneumococcal bacteria by detecting specific antibodies in your blood.

Quick summary

["It helps assess immunity after vaccination or natural exposure to pneumococcal strains."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42359-0
Short code
S pneum 14 serotypes IgG Pnl B Ser-mCnc
Synonyms
S pneum 14 serotypes IgG Pnl B Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to evaluate whether you have developed immunity against specific pneumococcal serotypes after receiving a pneumococcal vaccine or following an infection. It can also help monitor immune response in people with weakened immune systems or those at higher risk of pneumococcal diseases.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein, usually in your arm. You may feel a slight pinch, but it typically takes only a few minutes.

What the Test Results Mean

Results show the presence and level of antibodies against particular pneumococcal serotypes. Higher levels indicate a stronger immune response, while lower or absent levels suggest insufficient immunity. Interpretation depends on clinical context, such as vaccination history or symptoms.

Common Reasons for Testing

This test is often used in pediatric care to confirm vaccine effectiveness, in immunocompromised patients to track immune responses, or in research settings to study pneumococcal immunity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test helps identify if your immune system has produced protective antibodies against pneumococcal bacteria, which can cause serious infections like pneumonia, bloodstream infections, or meningitis. It is particularly useful for guiding vaccination strategies, monitoring immune function, and assessing risk in high-risk populations.

Short name

Pneumococcal IgG serotype antibodies

Frequently asked questions

Will this test show if I have pneumonia?
No, this test specifically measures antibodies to pneumococcal bacteria, not the presence of an active infection like pneumonia. If you suspect pneumonia or another infection, other tests or symptoms would guide diagnosis.
How long will I need to wait for results?
Results typically arrive within 1 to 3 business days, depending on lab processing times. Your healthcare provider will discuss findings with you during your follow-up visit.
Can I get this test if I’m pregnant?
Yes, this test is generally safe during pregnancy. However, always discuss any medical tests with your healthcare provider to ensure it aligns with your specific needs and safety.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy