Serotype-Specific Immunoglobulin (Ig) Antibody to Pneumococcal Neisseria meningitidis Serogroup
This test measures antibodies in your blood that target specific strains of pneumococcal bacteria, which can cause serious infections like pneumonia or meningitis. It helps assess immune response to vaccination or exposure to these bacteria.
["This test helps track your body’s reaction to pneumococcal vaccines or infections by detecting antibodies against specific bacterial serotypes."]
Key facts at a glance
- LOINC
- 42366-5
- Short code
- S pneum 23 serotypes IgG Pnl Ser-mCnc
- Synonyms
- S pneum 23 serotypes IgG Pnl Ser-mCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you’ve received a pneumococcal vaccine (like Prevnar or Pneumovax) and want to check if your immune system produced enough antibodies. It may also be used in research or clinical trials studying pneumococcal infections or vaccine effectiveness.
What to Expect Before the Test
No special preparation is needed. A blood sample will be drawn from a vein, typically in your arm. You may feel a slight pinch, but it usually takes only a few minutes. If you’re nervous, let your provider know so they can help make it more comfortable.
What the Test Results Mean
Results show the presence and level of antibodies against specific pneumococcal serotypes. High levels indicate a strong immune response, while low or absent levels suggest insufficient protection. Your provider will interpret these results in the context of your medical history and vaccination status.
Common Causes of Abnormal Results
Low antibody levels may mean your body didn’t respond well to vaccination, or you may have a weakened immune system. High levels could indicate recent infection or overactive immune response. Always discuss results with your provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is critical for monitoring vaccine effectiveness, diagnosing immune deficiencies affecting pneumococcal infections, and guiding treatment decisions in high-risk patients (e.g., those with chronic illnesses or asplenia). It also supports research into serotype-specific immunity and vaccine development.
Short name
Pneumococcal Serotype Antibodies (Serum)
Frequently asked questions
What does a positive result mean?
How long does it take to get results?
Can I get this test if I haven’t been vaccinated?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy