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Serological Testing for Pneumococcal Serotypes (IgG Antibody Levels)

Published: August 9, 2026Updated: August 16, 2026

This test measures your immune response to different types of *Streptococcus pneumoniae* (pneumococcal) bacteria by checking the levels of IgG antibodies against specific serotypes. It helps assess protection against pneumonia, meningitis, or other infections caused by these bacteria.

Quick summary

["This test helps determine if your immune system has developed protection against common pneumococcal strains."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42364-0
Short code
S pneum 6 serotypes IgG Pnl Ser-mCnc
Synonyms
S pneum 6 serotypes IgG Pnl Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have a history of pneumococcal infections, live in a high-risk setting (like a nursing home), have weakened immunity (e.g., from chemotherapy or HIV), or are planning travel to areas with higher infection risks. It may also be used to monitor immune response after vaccination.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein in your arm, similar to other blood tests. The process usually takes a few minutes, and you may feel a slight pinch or discomfort.

What the Results Mean

Results show the concentration of IgG antibodies against each pneumococcal serotype. Higher levels indicate stronger immunity to those specific strains. Interpretation depends on clinical context, such as vaccination history or symptoms.

Common Causes of Abnormal Results

Low antibody levels may suggest insufficient immunity, especially if you’ve received pneumococcal vaccines. High levels could indicate recent infection or immune response. Always discuss results with your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps evaluate immune protection against pneumococcal infections, guiding decisions about vaccination, preventive measures, or further medical evaluation. It’s particularly useful for high-risk individuals or those with compromised immune systems.

Short name

Pneumococcal Serotype Antibody Levels

Frequently asked questions

Why did my doctor order this test?
Your doctor may have recommended it to check if your immune system is protected against pneumococcal bacteria, especially if you’ve had infections, are at high risk, or need to travel to areas with higher infection rates.
What do my test results mean?
Results show your antibody levels against specific pneumococcal serotypes. A healthcare provider will explain what these levels indicate in your situation, considering factors like vaccination history or symptoms.
Can I get this test at home?
This test requires a blood sample, so it’s typically done in a clinical setting (like a doctor’s office or lab). No home testing is available for this specific test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy