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Serum Pneumococcal Serotype-Specific Immunoglobulin G Antibody Levels (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of antibodies against different types of *Pneumococcus* bacteria in your blood. These antibodies help your immune system recognize and fight infections caused by these bacteria.

Quick summary

["Your immune response to pneumococcal bacteria is assessed to understand protection against pneumonia or other infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42363-2
Short code
S pneum 7 serotypes IgG Pnl A Ser-mCnc
Synonyms
S pneum 7 serotypes IgG Pnl A Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a history of pneumococcal infections, live in a setting with high exposure (like a nursing home), or are at higher risk for complications from respiratory infections. It may also be used to evaluate immune function after vaccination or in certain chronic illnesses.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process is quick and typically painless. If you’re on blood thinners or have a history of bleeding issues, let your provider know beforehand.

What the Test Results Mean

Results show the concentration of antibodies against specific pneumococcal serotypes. Higher levels may indicate a strong immune response, while lower levels could suggest reduced protection. This information helps guide vaccination decisions or monitor immune function.

Common Reasons for Testing

This test is often used to assess immunity after receiving the pneumococcal vaccine (e.g., PCV13 or PPSV23) or to evaluate immune responses in individuals with weakened immune systems.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumococcal IgG Antibody Levels

Frequently asked questions

How Does This Test Help Healthcare Providers?
Healthcare providers use these results to determine if vaccination is needed, adjust treatment plans for immunocompromised patients, or monitor the effectiveness of preventive measures in high-risk populations.
What If My Results Are Low?
Low antibody levels may mean you’re not fully protected against pneumococcal infections. Your provider might recommend additional vaccinations, boosters, or further evaluation of your immune system.
How Often Should I Get This Test?
This test is typically not routine unless you’re at high risk or have been recently vaccinated. Follow your provider’s advice for follow-up testing based on your medical history and needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy