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Serum Pneumococcal Serotype-Specific Immunoglobulin G Antibody Levels (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of antibodies in your blood that target different types of *Pneumococcus* bacteria, a common cause of pneumonia, meningitis, and other infections.

Quick summary

["Helps assess immune response to pneumococcal vaccines or natural infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42362-4
Short code
S pneum 7 serotypes IgG Pnl B Ser-mCnc
Synonyms
S pneum 7 serotypes IgG Pnl B Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have a history of pneumococcal infections, are at higher risk (e.g., due to weakened immunity), or if you’ve received a pneumococcal vaccine. It can also help evaluate immune function in certain conditions.

What to Expect Before the Test

No special preparation is needed. A blood sample is drawn from a vein, typically in your arm. The test is usually done in a lab and results may take several days to weeks.

What the Results Mean

Results show the concentration of antibodies against specific pneumococcal serotypes. Higher levels indicate a stronger immune response, while lower levels may suggest insufficient protection.

Common Reasons for Testing

This test is often used to monitor immune responses after vaccination, diagnose immune deficiencies, or evaluate the effectiveness of treatments for recurrent infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated antibody levels against certain serotypes may indicate past infection or vaccination success. Low levels could signal immune system issues or inadequate vaccine response, guiding further medical evaluation.

Short name

Pneumococcal Antibody Levels

Frequently asked questions

How long does it take to get results?
Results typically take 1–2 weeks or longer, depending on lab processing times. Your healthcare provider will discuss them with you during follow-up.
Can I eat or drink before this test?
No special diet or fasting is required. You may eat and drink normally before the blood draw.
What does it mean if my antibody levels are low?
Low levels may suggest a weaker immune response to pneumococcal antigens, which could be due to vaccination history, immune disorders, or other health factors. Your doctor will interpret results in the context of your medical history.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy