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Serum or Plasma Nitrogenous Substance Concentration (General Protein or Amino Acid Profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of various nitrogenous compounds in your blood, which may include proteins, amino acids, or other soluble substances. It helps assess overall protein status, kidney function, or metabolic health.

Quick summary

["This test provides insights into your blood chemistry and can help identify issues with protein metabolism or kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111010-5
Short code
S pneum Ab Msmt Ser
Synonyms
S pneum Ab Msmt Ser
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test typically includes measurements of key nitrogenous substances, such as albumin, globulins, amino acids (e.g., alanine, glutamine), and other proteins. Some panels may also evaluate electrolytes or metabolic byproducts. Results are often reported as concentrations in milligrams per deciliter (mg/dL) or grams per liter (g/L), depending on the specific analytes included.

Why It Matters in Your Health

High or low levels of certain nitrogenous substances can signal underlying conditions, such as malnutrition, liver disease, kidney problems, or metabolic disorders. For example, low albumin may indicate poor nutrition or liver dysfunction, while abnormal amino acid levels could hint at metabolic imbalances.

Common Uses

Doctors may order this test to evaluate protein status in patients with chronic illnesses, monitor kidney function, assess nutritional deficiencies, or diagnose metabolic disorders. It can also help guide treatment plans for conditions like liver disease or severe infections.

Preparation Tips

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it includes certain components (e.g., amino acid profiles). Avoid excessive alcohol or caffeine on the day of testing. Your doctor will provide specific instructions if applicable.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

How long will I need to wait for my results?
Results are typically available within 1–3 business days, depending on the lab’s processing time and whether additional confirmatory testing is needed. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
Most general protein or amino acid tests do not require fasting, but if your test includes specific components (e.g., glucose or electrolytes), your doctor may advise fasting. Always follow their instructions to ensure accurate results.
What does it mean if my results are outside the normal range?
Abnormal results may indicate conditions like malnutrition, kidney disease, liver problems, or metabolic disorders. Your doctor will interpret the results in the context of your medical history and symptoms to determine the next steps, which could include further testing or treatment adjustments.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy