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Serum or plasma mass concentration of pneumococcal polysaccharide antibodies (e.g., capsular polysaccharides)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of antibodies your body produces in response to pneumococcal bacteria, which can cause serious infections like pneumonia or bloodstream infections.

Quick summary

["Helps assess immune response to pneumococcal vaccines or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25531-5
Short code
S pneum Ab Ser-mCnc
Synonyms
S pneum Ab Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test detects specific antibodies against pneumococcal bacteria, which are often used to evaluate immunity after vaccination or to monitor immune function in people at higher risk of pneumococcal infections.

Why It Might Be Ordered

Your healthcare provider may order this test if you’ve received a pneumococcal vaccine, have a history of recurrent infections, or are at increased risk (e.g., due to weakened immunity, certain medical conditions, or living in close quarters).

How the Test Works

Blood is drawn and analyzed to measure the concentration of antibodies targeting pneumococcal polysaccharides. The method may involve immunoassay techniques to detect and quantify these antibodies.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to avoid certain medications or supplements that could affect test results. Always follow your provider’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumococcal Antibody Level

Frequently asked questions

High antibody levels may indicate a strong immune response to vaccination or infection, while low levels could suggest insufficient immunity, requiring further evaluation or booster doses.
This test helps determine if vaccination has been effective or if immune protection needs reinforcement, especially in high-risk individuals.
What Are Normal Results?
There are no universally standardized reference ranges for this specific antibody measurement, as levels can vary based on vaccination history, age, and immune status. Your results will be interpreted by your healthcare provider in context.
Can This Test Be Done at Home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy