Cerebrospinal Fluid Protein (Total Protein) by Electrophoresis

Why This Test Is Done

Your doctor may order this test if you have symptoms like headaches, neck stiffness, confusion, or neurological problems that suggest conditions like meningitis, multiple sclerosis, or brain tumors. It’s also used to monitor certain treatments or diagnose conditions affecting the CSF.

What to Expect Before the Test

You’ll likely have a lumbar puncture (spinal tap) where a small needle is inserted into your lower back to collect CSF. The procedure is quick but may cause mild discomfort. No special preparation is needed, but inform your doctor about any medications or allergies.

What the Results Mean

Protein levels in CSF can vary widely based on health, age, and underlying conditions. Elevated levels may indicate inflammation, infection, or blood leakage into the CSF. Lower levels might suggest certain genetic or metabolic disorders. Your doctor will interpret results in the context of your symptoms and medical history.

Common Conditions Affecting Results

High protein levels can be seen in conditions like meningitis, multiple sclerosis, or brain tumors. Low protein levels may occur in rare genetic disorders or certain metabolic diseases. Always discuss your results with your healthcare provider.