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Serum or Plasma Substance Concentration for Pneumococcal Polysaccharide Antigen (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of pneumococcal polysaccharide antigens in your blood, which can help identify if you have an infection caused by *Streptococcus pneumoniae* (pneumococcus).

Quick summary

["A positive result may indicate active pneumococcal infection requiring prompt medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17652-9
Short code
S pneum Ag Spec Ql LA
Synonyms
S pneum Ag Spec Ql LA
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
la
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for specific antigens produced by *Streptococcus pneumoniae*, a common cause of pneumonia, meningitis, and other serious infections. These antigens are fragments of the bacteria’s outer coat that the immune system recognizes. If present in your blood, they suggest recent bacterial infection.

Why It’s Done

Your healthcare provider may order this test if you have symptoms like high fever, chest pain, confusion, or severe headache—especially if you’re at higher risk for pneumococcal infections (e.g., elderly adults, people with weakened immune systems, or those with chronic health conditions).

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum or plasma (the liquid part without clotting factors) for testing. This test does not require fasting.

Test Limitations

This is a qualitative test, meaning it only tells you *if* the antigen is present, not how much. Results may not be available immediately, and false positives or negatives can occur, especially in early or late stages of infection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumococcal Antigen Screen (Serum/Plasma)

Frequently asked questions

When might I get this test?
Your doctor may recommend it if you have symptoms of a serious bacterial infection, such as pneumonia, meningitis, or sepsis, and you’re at higher risk for pneumococcal disease.
What does a positive result mean?
A positive result means your blood contains pneumococcal antigens, indicating a likely bacterial infection caused by *Streptococcus pneumoniae*. This requires urgent medical evaluation to guide treatment, such as antibiotics.
Can I eat or drink before this test?
No special preparation is needed. You can eat, drink, or take medications as usual, as this test does not require fasting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy