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Serum or Plasma Substance Concentration (Qualitative) for Pneumococcal Antigen

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of *Pneumococcus* bacteria antigens in your blood or plasma, which can help identify infections caused by this common bacterial cause of pneumonia, meningitis, or other serious illnesses.

Quick summary

["Helps diagnose pneumococcal infections early, when prompt treatment is critical."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24027-5
Short code
S pneum Ag Ur Ql
Synonyms
S pneum Ag Ur Ql
Category
coagulation
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for specific antigens produced by *Pneumococcus* bacteria in your blood or plasma. These antigens are unique markers that can confirm a pneumococcal infection, even before symptoms become severe. This is particularly useful for patients at high risk, such as those with weakened immune systems or chronic health conditions.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms like high fever, difficulty breathing, or rapid onset of severe illness, especially if you’ve been exposed to someone with a pneumococcal infection. It’s also used in high-risk groups, like children under 2, elderly adults, or those with diseases like diabetes or heart conditions.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is then processed to separate the serum or plasma (the liquid part of blood without clots). This sample is tested for the presence of pneumococcal antigens using a sensitive immunoassay method.

What to Expect Before the Test

No special preparation is needed, but inform your provider if you’re on blood-thinning medications or have a history of bleeding disorders. Avoid alcohol for 24 hours before testing if instructed, as it may affect blood clotting.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result strongly suggests a pneumococcal infection and can guide urgent treatment with antibiotics targeting *Pneumococcus*. This test is especially valuable in cases where traditional blood cultures may take days to confirm. It helps reduce unnecessary antibiotic use in cases where the infection is unlikely, saving time and resources.

Short name

Pneumococcal Antigen Screening (Serum/Plasma)

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your provider will discuss the results with you during a follow-up visit.
Can I have this test if I’m pregnant?
Yes, this test is safe to have during pregnancy. Pneumococcal infections can pose risks to both mother and baby, so early detection is important. Always discuss your test with your healthcare provider to ensure it’s appropriate for your situation.
What if my test is negative but I still feel sick?
A negative result means no pneumococcal antigens were detected in your sample at the time of testing. However, infections can develop quickly, so symptoms may persist. If you continue to feel unwell, consult your provider to explore other possible causes or repeat testing if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy