Serum or Plasma Protein Electrophoresis by Bromocresol Green (BCG) Method
This test measures the distribution of different protein fractions in your blood, including albumin and globulins, using a dye called bromocresol green. It helps assess conditions affecting protein balance, such as liver disease or kidney problems.
["This test helps identify protein abnormalities that may signal underlying health issues."]
Key facts at a glance
- LOINC
- 85972-8
- Short code
- S pneum Da 12F Ab Ser-aCnc
- Synonyms
- S pneum Da 12F Ab Ser-aCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Proteins Does This Test Measure?
Your blood contains several types of proteins, including albumin (the most abundant) and various globulins (like immunoglobulins). The BCG electrophoresis method separates these proteins based on size and charge, allowing for detailed analysis of their concentrations. This can reveal imbalances that might indicate conditions like chronic liver disease, kidney dysfunction, or certain immune disorders.
Why Might Your Doctor Order This Test?
Doctors may request this test if you have symptoms like swelling, unexplained weight loss, fatigue, or if they suspect conditions such as multiple myeloma, liver disease, or severe infections. It’s also used to monitor protein levels in patients receiving certain treatments.
How Is the Sample Collected?
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum or plasma for testing. No special preparation is needed, but fasting may be advised depending on your specific situation.
What Are Common Results and Next Steps?
Results may show shifts in protein bands, indicating abnormal protein levels. For example, low albumin might suggest liver or kidney disease, while unusual globulin patterns could signal immune system issues. Your doctor will discuss findings with you and may recommend further testing or treatments based on your results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test plays a key role in diagnosing and managing conditions that disrupt protein synthesis or retention, such as liver cirrhosis, nephrotic syndrome, or monoclonal gammopathy. It can also help monitor disease progression or response to treatment by tracking protein changes over time.
Short name
BCG Protein Electrophoresis
Frequently asked questions
What does a protein electrophoresis test measure?
How long does it take to get results from this test?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy