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Serum or plasma concentration of immunoglobulin G (IgG) antibodies against pneumococcal polysaccharides (qualitative or semi-quantitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures whether your body has produced antibodies to certain bacteria called pneumococci, which can cause serious infections like pneumonia, bloodstream infections, or meningitis.

Quick summary

["Helps identify if your immune system has recognized pneumococcal bacteria, useful in assessing risk for infections or evaluating immune response after vaccination."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85973-6
Short code
S pneum Da 12F Ab Ser Ql
Synonyms
S pneum Da 12F Ab Ser Ql
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test detects the presence of specific antibodies (IgG) your immune system produces in response to exposure to pneumococcal bacteria. These antibodies are part of your body’s defense mechanism against these bacteria, which can cause infections in the lungs, sinuses, or bloodstream.

Why It Might Be Ordered

Your healthcare provider may order this test if you have a history of pneumococcal infections, are at high risk (e.g., due to weakened immune systems, chronic illnesses, or age), or if you’re considering vaccination to prevent pneumococcal disease.

What to Expect Before the Test

No special preparation is needed. You may have a simple blood draw, where a small amount of blood is taken from a vein in your arm. If you’re taking blood from a different site (like a fingerstick), a small amount of urine or saliva might be used instead.

What to Expect During the Test

The test involves drawing a small sample of blood, urine, or saliva to check for antibodies. Results are typically available within a few days, depending on lab processing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate your immune system has detected and produced antibodies against pneumococcal bacteria, which may suggest past exposure or vaccination. Negative results mean no detectable antibodies, which could mean you haven’t been exposed or vaccinated yet. This can guide decisions about vaccination or further monitoring.

Short name

Pneumococcal Antibody Screening (IgG)

Frequently asked questions

What does a positive result mean?
A positive result suggests your body has recognized pneumococcal bacteria, either through past infection or vaccination. This may help your healthcare provider assess your risk for future infections or guide vaccination recommendations.
What if my test is negative?
A negative result means your body did not produce detectable antibodies against these bacteria at the time of testing. This could mean you haven’t been exposed or vaccinated yet, so your healthcare provider may recommend vaccination or further monitoring if you’re at high risk.
Does this test replace a vaccine?
No, this test is not a substitute for vaccination. It helps determine if you’ve had exposure or developed immunity, but vaccination remains the best way to prevent pneumococcal infections.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy