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Serum Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green dye binds to proteins in your serum, which can help assess liver function and protein synthesis.

Quick summary

["This test evaluates liver health by tracking protein binding capacity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85975-1
Short code
S pneum Da 12F IgG Ser-aCnc
Synonyms
S pneum Da 12F IgG Ser-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Bromocresol green (BCG) is a dye that binds to albumin and other proteins in your blood. When your liver produces fewer proteins, less dye binds. This test quantifies how much dye remains unbound in your serum, reflecting overall protein levels and liver function.

Why It’s Done

Doctors may order this test to check for liver disease, malnutrition, or protein-related conditions. It can also help monitor treatment progress in patients with chronic liver issues or kidney disease.

How It Works

A blood sample is drawn, and the serum is tested for its ability to bind BCG dye. The unbound dye concentration is measured, which indirectly indicates protein levels and liver function capacity.

Preparation Tips

No special preparation is needed, but avoid heavy meals or alcohol before testing if instructed by your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Dye Binding Assay (Serum)

Frequently asked questions

What does a low or high result mean?
Low results may suggest liver disease, malnutrition, or severe protein loss, while high results could indicate overproduction of proteins or certain metabolic conditions. Always discuss results with your healthcare provider.
Can this test detect liver cancer?
No, this test is not specific for liver cancer. It primarily assesses protein synthesis and liver function but isn’t used for cancer diagnosis.
How often should I get this test?
Frequency depends on your health condition. Your doctor will determine if regular monitoring is needed, such as for chronic liver disease or kidney issues.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy