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Serum or plasma mass concentration of pneumococcal polysaccharide (e.g., capsular polysaccharide from *Streptococcus pneumoniae*)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of pneumococcal polysaccharides in your blood, which may help assess immune response to *Streptococcus pneumoniae* (pneumococcus) infection or vaccination.

Quick summary

["Helps evaluate immune function and response to pneumococcal vaccines or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85952-0
Short code
S pneum Da 1 Ab Ser-mCnc
Synonyms
S pneum Da 1 Ab Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have concerns about immune function, especially after receiving a pneumococcal vaccine, or if you’re at higher risk for pneumococcal infections (e.g., due to weakened immunity, chronic conditions, or recent illness). It may also be used to monitor immune response in certain clinical settings.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from a vein in your arm. The sample is then processed to measure the polysaccharide concentration.

What the Results Mean

Results are qualitative (present/absent) or quantitative (mass concentration in units like mg/L), depending on the method. Higher levels may indicate recent infection or vaccination response, while low or absent levels may suggest immune deficiency or inadequate response.

Common Reasons for Testing

This test is less commonly performed in routine clinical practice but may be used in specialized settings like research, vaccine trials, or patients with suspected immune disorders linked to pneumococcal exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Role in Diagnosis and Monitoring

Short name

Pneumococcal Polysaccharide Level

Frequently asked questions

Is this test used to diagnose pneumococcal infections?
No, this test is not typically used for diagnosing active pneumococcal infections. Instead, it may be part of broader immune evaluations or research studies focused on pneumococcal polysaccharides.
Can this test help determine if I had an effective pneumococcal vaccine?
Yes, in some cases, measuring polysaccharide levels can help assess whether your immune system responded appropriately to pneumococcal vaccination, though this is not standard practice for routine vaccination follow-ups.
What should I do if my test results are abnormal?
If results are abnormal, discuss them with your healthcare provider. They may recommend further testing, adjustments to treatment, or additional evaluations to understand the cause (e.g., infection, immune response, or lab error).
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy