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Protein Electrophoresis, Serum (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood serum using electrophoresis, a technique that separates proteins based on size and charge.

Quick summary

["Helps identify abnormal protein patterns that may indicate conditions like multiple myeloma or other blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85747-4
Short code
S pneum Da 1 DNA Ct Spec Qn NAA+probe
Synonyms
S pneum Da 1 DNA Ct Spec Qn NAA+probe
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Proteins Are Measured?

Electrophoresis separates proteins into five main bands: albumin, alpha-1 globulins, alpha-2 globulins, beta globulins, and gamma globulins. Each band represents a group of proteins with similar electrical charges and sizes. Abnormal patterns may suggest conditions affecting protein production or function.

Common Uses and Conditions

This test is often used to diagnose or monitor conditions such as multiple myeloma (a cancer of plasma cells), Waldenström macroglobulinemia, and other disorders involving abnormal protein production. It may also help evaluate liver or kidney disease, as these organs can affect protein levels.

Preparation for the Test

No special preparation is needed for this test. You may eat and drink normally before your blood draw. Your healthcare provider will explain how to prepare if you have any specific instructions.

What to Expect During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch or discomfort, but it usually lasts only a few seconds. The process is quick, and you can return to your normal activities immediately afterward.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein patterns detected in electrophoresis can indicate underlying health issues. For example, elevated gamma globulins may suggest multiple myeloma or other plasma cell disorders. Low albumin levels might point to liver disease or malnutrition. Your healthcare provider will interpret the results in the context of your overall health and symptoms.

Short name

Protein Electrophoresis

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if they suspect conditions like multiple myeloma, kidney disease, liver disease, or certain autoimmune disorders. It can also be used to monitor treatment progress for conditions affecting protein levels.
What do abnormal results mean?
Abnormal results could show unusual protein patterns, such as spikes (monoclonal bands) that may indicate cancer or other disorders. Low albumin levels might suggest liver or kidney problems. Always discuss your results with your healthcare provider, as they will explain what they mean for your specific situation.
How often will I need this test?
The frequency of this test depends on your health condition and treatment plan. If you have a chronic condition like multiple myeloma, your doctor may order follow-up tests regularly to monitor changes in your protein levels. Ask your healthcare provider for details tailored to your needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy