Serum Immunoassay for Anti-Neutrophil Cytoplasmic Antibodies (ANCA) – p-ANCA
This blood test measures a type of antibody called anti-neutrophil cytoplasmic antibody (p-ANCA), which may indicate inflammation in certain autoimmune conditions.
["p-ANCA antibodies can help diagnose conditions like vasculitis or other inflammatory diseases."]
Key facts at a glance
- LOINC
- 86058-5
- Short code
- S pneum Da 22F IgG 2:1 Ser-Rto
- Synonyms
- S pneum Da 22F IgG 2:1 Ser-Rto
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is p-ANCA Used For?
p-ANCA tests are primarily used to help identify people with certain types of vasculitis, a group of rare but serious conditions where blood vessels become inflamed. This test may also support the diagnosis of autoimmune diseases affecting the kidneys, lungs, or skin.
How Is the Test Performed?
A blood sample is drawn from your arm, and the serum (liquid part of blood) is sent to a lab for testing using an immunoassay method. This detects the presence of p-ANCA antibodies in your blood.
What Does a Positive Result Mean?
A positive p-ANCA result suggests a higher likelihood of vasculitis or related inflammatory conditions, but it does not confirm a diagnosis alone. Your healthcare provider will consider the result alongside other tests and symptoms to make a full assessment.
When Might You Need This Test?
You may need a p-ANCA test if you have symptoms like unexplained skin rashes, joint pain, kidney issues, or unexplained inflammation. Doctors often order it for people with suspected vasculitis or other autoimmune conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
p-ANCA antibodies are linked to conditions like granulomatosis with polyangiitis (GPA) or microscopic polyangiitis, which can affect blood vessels in organs. While not all positive results indicate disease, they signal a need for further evaluation to rule out serious inflammatory or autoimmune disorders.
Short name
p-ANCA Antibody Test
Frequently asked questions
Why might my doctor order a p-ANCA test if I don’t have symptoms?
Can p-ANCA test results change over time?
What if my p-ANCA test is negative but I still have symptoms?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy