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Immunoglobulin G (IgG) in Serum, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody found in your blood serum. IgG helps protect your body from infections and is important for long-term immunity.

Quick summary

["IgG helps fight infections and supports long-term immunity by binding to pathogens."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86041-1
Short code
S pneum Da 2 IgG sp1 Ser-mCnc
Synonyms
S pneum Da 2 IgG sp1 Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin G (IgG)?

IgG is the most common type of antibody in your blood. Antibodies are proteins that help your immune system recognize and fight off harmful substances like bacteria and viruses. IgG is particularly important because it can cross the placenta to provide passive immunity to your baby during pregnancy and shortly after birth. It also remains in your body for a long time, providing ongoing protection against infections you’ve already encountered.

Why Might You Need This Test?

Doctors may order an IgG test to evaluate your immune system function. This could be done if you have symptoms of a weakened immune system, such as frequent infections, slow healing wounds, or unexplained fatigue. It may also be used to monitor conditions like autoimmune diseases, certain infections, or to check for immune deficiencies before or after treatments like chemotherapy.

When Could You Expect Results?

The results of your IgG test are typically available within a few days after your blood sample is drawn. Your healthcare provider will discuss the results with you and explain what they mean in the context of your health.

What Can Affect IgG Levels?

Several factors can influence IgG levels, including your overall health, immune status, diet, and certain medications. Chronic illnesses, infections, or autoimmune conditions can sometimes lead to lower IgG levels, while certain treatments or nutritional deficiencies may affect production.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgG levels can provide important clues about your immune health. Low IgG levels may indicate an immune deficiency or a condition that affects antibody production, such as HIV/AIDS, certain cancers, or long-term use of immunosuppressive medications. High IgG levels might be seen in chronic infections, autoimmune diseases, or certain allergic reactions. Your doctor will use these results along with other factors to guide diagnosis and treatment.

Short name

IgG Level

Frequently asked questions

How is this test typically performed?
A small amount of blood is drawn from a vein in your arm. The blood sample is then sent to a lab where it is processed to separate the serum (the liquid part of blood without clots). The IgG antibody is measured using a specialized immunoassay technique that detects its presence and concentration.
Will this test hurt?
You may feel a slight pinch or sting when the needle is inserted, but the procedure is generally quick and well-tolerated. Most people experience minimal discomfort afterward.
Can I eat or drink before this test?
You can usually eat and drink normally before this test unless your doctor has specific instructions. Some tests may require fasting, but this IgG test does not.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy