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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green (BCG) binds to a protein in your blood, often used to assess liver function or protein synthesis.

Quick summary

["This test helps evaluate liver health and protein balance in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86097-3
Short code
S pneum Da 3 Ab 2:1 Ser-Rto
Synonyms
S pneum Da 3 Ab 2:1 Ser-Rto
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The BCG dye binding test works by exposing a sample of your blood to bromocresol green dye. Healthy proteins in your blood, particularly those produced by the liver, bind to the dye. The amount of dye bound is measured to estimate protein levels or liver function capacity.

Why It’s Done

Doctors may order this test to check for liver disease, protein deficiencies, or other conditions affecting protein synthesis. It can also be part of routine monitoring for patients with chronic liver conditions or those receiving treatments that impact protein metabolism.

Common Uses and Conditions

This test is sometimes used in research or specialized clinical settings to assess protein binding capacity, though it is less common than other liver function tests like ALT or albumin measurements.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The sample is then processed to separate serum or plasma for testing. This test does not require fasting unless specified by your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Dye Binding Test

Frequently asked questions

This test can provide insight into liver function and protein production, though it is not as widely used as standard liver function tests. Abnormal results may indicate liver disease, malnutrition, or other metabolic issues requiring further evaluation.
This test may not be covered by all insurance plans, and costs can vary. Always confirm with your healthcare provider or lab about payment details.
What does a high or low result mean?
Results can be interpreted in the context of your overall health and other tests. High levels might suggest certain liver conditions or protein disorders, while low levels could indicate malnutrition or liver dysfunction. Your doctor will discuss findings with you.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on the lab. Follow-up with your healthcare provider to discuss any abnormal findings.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy