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Serum or plasma *Antibody to Streptococcus pneumoniae (IgG) by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies your body produces in response to *Streptococcus pneumoniae* (pneumococcus), a common bacteria that can cause pneumonia, ear infections, or bloodstream infections.

Quick summary

["Helps assess past or current infection risk and immune response to pneumococcal bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85741-7
Short code
S pneum Da 4 DNA Ct Spec Qn NAA+probe
Synonyms
S pneum Da 4 DNA Ct Spec Qn NAA+probe
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of pneumonia, recurrent infections, or if you’re at higher risk for pneumococcal infections (e.g., due to weakened immune system, age, or chronic conditions like diabetes or heart disease). It may also be used to evaluate immune response after vaccination or monitor long-term exposure.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein, usually in your arm. If you’re taking blood thinners, let your provider know to avoid unnecessary bleeding.

What the Test Results Mean

Higher levels of antibodies suggest your body has recognized and fought off pneumococcal bacteria. Lower or absent levels may indicate no prior exposure or a weakened immune response. Results are interpreted by your healthcare provider based on your medical history and symptoms.

Common Conditions Monitored

This test can help diagnose or evaluate conditions like pneumonia, sinusitis, or other infections caused by pneumococcal bacteria. It may also be used in research or clinical trials studying immune responses to pneumococcal vaccines.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Strep pneumoniae antibody test

Frequently asked questions

What does elevated antibody levels mean?
Elevated antibody levels indicate your immune system has detected and responded to pneumococcal bacteria, which may be useful in diagnosing past infections or assessing immune function. However, elevated levels alone don’t confirm active infection without clinical symptoms or other diagnostic tests.
Can this test replace a culture?
No. While this test measures antibodies, it doesn’t identify the specific bacteria causing an infection. A bacterial culture is needed to confirm the presence of *Streptococcus pneumoniae* or other pathogens.
How often should I get this test?
Your provider will determine the frequency based on your health needs, symptoms, or vaccination status. Routine testing isn’t typically recommended unless you have specific risk factors or clinical indications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy