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Serum Immunoglobulin G (IgG) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and is important for long-term immunity.

Quick summary

["IgG levels help assess immune function and detect potential deficiencies or abnormalities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109042-2
Short code
S pneum Da 6A IgG Msmt Ser
Synonyms
S pneum Da 6A IgG Msmt Ser
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgG Measure?

IgG is the most common type of antibody in your blood. It plays a key role in fighting off infections by helping your immune system recognize and remember pathogens like bacteria and viruses. IgG also helps transfer immunity from mother to baby during pregnancy.

Why Might You Need This Test?

Doctors may order an IgG test to check for immune system issues, such as low levels that could indicate conditions like HIV, certain cancers, or autoimmune diseases. It may also be used to monitor immune responses after vaccination or treatment for infections.

Sample Collection and Preparation

This test requires a blood sample drawn from a vein in your arm. After drawing blood, it is sent to a lab where it is processed to separate the serum (the liquid part without clots). The serum is then analyzed to measure IgG levels.

What to Expect Before the Test

No special preparation is needed for this test. You can eat and drink normally on the day of your appointment. If you are on blood-thinning medication, let your healthcare provider know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low IgG levels may suggest an immune deficiency, chronic illness, or conditions like celiac disease or malabsorption syndromes. High IgG levels can sometimes indicate chronic infections, inflammatory conditions, or certain cancers. Monitoring IgG levels helps guide treatment decisions and manage long-term health.

Short name

IgG Level

Frequently asked questions

How long does it take to get results?
Results are typically available within a few days to a couple of weeks, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
What does a low IgG level mean?
A low IgG level might mean your immune system isn’t working as well as it should, which can increase your risk of infections. This could be due to genetic conditions, certain medications, or chronic illnesses. Your doctor will determine the best course of action based on your overall health and symptoms.
Can IgG levels change over time?
Yes, IgG levels can fluctuate due to factors like infections, vaccinations, aging, or certain medical conditions. Regular monitoring may be needed if you have an ongoing health issue affecting your immune system, such as HIV or autoimmune diseases.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy