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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green dye binds to a protein in your blood, often used to assess liver function or protein synthesis.

Quick summary

["This test helps evaluate liver health and protein balance in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13167-2
Short code
S pneum Da 7F Ab Ser-aCnc
Synonyms
S pneum Da 7F Ab Ser-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses bromocresol green dye, which binds to certain proteins in your blood. When the dye binds, it changes color, allowing the lab to determine how much protein is present. This method is particularly useful for detecting changes in protein levels, which can reflect liver function or other metabolic processes.

Why It’s Done

Your healthcare provider may order this test if you have symptoms like fatigue, jaundice (yellowing of skin/eyes), or if they suspect liver disease, protein deficiency, or other conditions affecting protein synthesis.

Common Conditions Monitored

This test is sometimes used to monitor conditions like hypoalbuminemia (low protein levels), liver cirrhosis, or other liver-related disorders. It may also be part of routine liver function panels in certain clinical settings.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma, which is sent to the lab for testing. The lab will analyze the dye binding properties of the protein fraction.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Changes in bromocresol green binding can indicate liver dysfunction, reduced protein synthesis, or other metabolic disturbances. While less commonly used today, it remains a historical method for assessing protein-related liver function. Results may be compared to baseline or other liver tests for context.

Short name

BCG Dye Binding Test

Frequently asked questions

What does a high or low result mean?
A high result may suggest normal or slightly altered protein levels, but it’s not a definitive indicator of liver disease. A low result could signal liver problems or protein loss, but further tests may be needed to confirm.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Follow up with your provider if you have questions about your results.
Is this test covered by insurance?
Check with your insurance provider to confirm coverage, as this test may not be routinely included in standard liver function panels. Your provider can clarify if it’s medically necessary for your situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy