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Serum or plasma mass concentration of pneumococcal polysaccharide antigen (by immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of pneumococcal polysaccharide antigen in your blood. It helps assess immune response after vaccination or in certain infections.

Quick summary

["This test may help check if your body produced enough antibodies after a pneumococcal vaccine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25296-5
Short code
S pneum Da 7F IgG Ser-mCnc
Synonyms
S pneum Da 7F IgG Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’ve received a pneumococcal vaccine (such as Prevnar or Pneumovax) and want to check if your immune system responded well. It may also be used in research or specialized clinical settings to monitor immune function related to pneumococcal infections.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein, typically in your arm. The test uses a small amount of serum or plasma to measure the antigen level.

What the Results Mean

Results are qualitative (present or absent) rather than numeric. A positive result means detectable levels of the antigen, which may indicate an immune response or infection. A negative result suggests no detectable antigen.

Common Reasons for Testing

This test is less commonly performed in routine clinical practice but may be used in specific cases, such as evaluating vaccine efficacy in high-risk individuals or studying immune responses in research studies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumococcal Polysaccharide Antigen Level

Frequently asked questions

What does a positive result mean?
A positive result means the test detected the presence of pneumococcal polysaccharide antigen in your blood. This could indicate an immune response after vaccination or, in some cases, an infection. Your healthcare provider will interpret results in the context of your medical history and symptoms.
Is this test covered by insurance?
Coverage depends on your insurance plan and the clinical reason for testing. Since this test is not widely used in standard care, check with your insurance provider or healthcare provider to confirm coverage details.
How long does it take to get results?
Results are typically available within a few days to a week, depending on laboratory processing times and testing methods. Your healthcare provider will contact you once results are ready.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy