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Serum or Plasma Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood, separated by size and charge, to help identify abnormalities such as infections, diseases like multiple myeloma, or other conditions affecting protein production.

Quick summary

["Protein electrophoresis helps diagnose and monitor conditions by revealing unusual protein patterns in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86145-0
Short code
S pneum Da 8 Ab Ser-aCnc
Synonyms
S pneum Da 8 Ab Ser-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or signs of a blood disorder. It’s also used to monitor conditions like multiple myeloma, lymphoma, or kidney disease, where protein levels can change over time.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood, or your healthcare provider may collect a sample from a vein in your arm. If you’re fasting, follow your provider’s instructions.

What the Test Results Mean

Results show bands representing different protein groups (e.g., albumin, globulins). Abnormal bands or patterns may indicate conditions like infections, inflammation, or protein disorders. Your provider will interpret results in the context of your symptoms and medical history.

Common Conditions Monitored

This test helps diagnose or track conditions such as multiple myeloma (a cancer of plasma cells), chronic kidney disease, liver disease, or autoimmune disorders. It can also detect signs of severe infections or nutritional deficiencies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How long will I need to wait for my results?
Results are typically available within 24 to 72 hours, depending on lab processing times. Your healthcare provider will contact you directly with findings, so check in with them if you haven’t heard back sooner.
Can I eat or drink before this test?
No fasting is required for this test. However, if you’re scheduled for a related blood test that does require fasting, follow your provider’s instructions for that specific test.
What does it feel like to have blood drawn?
Most people experience a brief pinch or sting when the needle is inserted. Some may feel lightheaded or dizzy, but this usually passes quickly. You can ask your healthcare provider about ways to reduce discomfort, such as choosing a different vein or using a tourniquet.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy